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Of the 314 patients randomized to OPDIVO administered with ipilimumab in Trial 7, 41% were 65 years or older and 11% were 75 years or older.
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Treatment is mandatory in patients aged over 65 years and in patients with associated comorbidities (such as heart disease or osteoporosis) or symptoms suggestive of hyperthyroidism (see section 5).
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The most common reason for interstitial disease is from an allergic reaction to a drug, but it can also be brought on by infection or autoimmune disease.
TSH receptor mutation leading to functional hypersensitivity to hCG also has been recognized as a rare cause of gestational hyperthyroidism ().
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The doctor may ask you to cover one ear at a time to see how well you hear words spoken at various volumes and how you respond to other sounds.
NIHSS for deficit and modified Rankin Scale (mRS) for functional outcome were used.
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Cure of the hyperthyroidism and a restoration of the euthyroid state frequently results in a reversion of the atrial fibrillation to sinus rhythm and a resolution of the cardiac manifestations ().
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