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I work as an ornithologist - I study birds and their habitat. Africe is the best place on Earth to study these graceful creatures as nowhere else you will see such a diversity and brightfulness of birds. Every year I go to Africa and nearby islands at least twice and every time I have to think about my health before I go. Usually I take Chloroquine and it helps me keep away from malaria which is very common in Africa. I never experienced any of the side effects from similar medications that people claim about. I think I owe to this drug for still being able to do my beloved job and stay healthy and happy.
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The team screened approximately 1000 already approved FDA compounds and discovered that two anti-malaria drugs (chloroquine and amodiaquine) act at Nurr1 (3).
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It is highly effective as a suppressive agent in patients with vivax or malariae malaria, in terminating acute attacks, and significantly lengthening the interval between treatment and relapse.
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Research on the mechanism of chloroquine and how the parasite has acquired chloroquine resistance is still ongoing, as other mechanisms of resistance are likely.
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When chloroquine is used for prolonged period it is important to get periodic eye examination and laboratory test (complete blood picture, liver functions test) done to look for side effects.
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Most recently, a low-grade resistance to artemisinin-based drugs has emerged in parts of Southeast Asia.
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The fungus that causes asper, Aspergillus fumigates, is found everywhere except the frozen arctic and Antarctic regions; birds are constantly exposed to it.
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No drug treatment is completely effective in preventing malaria.
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As mentioned above, Chloroquine can cause damage to the back of the eye (retina).
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Artemisinin (the plant's active component) and its synthetic derivatives have proved to be very effective treatments in persons infected with otherwise resistant Plasmodium strains, and they may have additional potential as prophylactic agents.
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